Nonhomologous end joining and V(D)J recombination require an additional factor

DNA nonhomologous end-joining (NHEJ) is the major pathway for repairing DNA double-strand breaks in mammalian cells. It also functions to carry out rearrangements at the specialized breaks introduced during V(D)J recombination. Here, we describe a patient with T(−)B(−) severe combined immunodeficien...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Dai, Y., Kysela, B., Hanakahi, L. A., Manolis, K., Riballo, E., Stumm, M., Harville, T. O., West, S. C., Oettinger, M. A., Jeggo, P. A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12604777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437964100
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