Nonhomologous end joining and V(D)J recombination require an additional factor
DNA nonhomologous end-joining (NHEJ) is the major pathway for repairing DNA double-strand breaks in mammalian cells. It also functions to carry out rearrangements at the specialized breaks introduced during V(D)J recombination. Here, we describe a patient with T(−)B(−) severe combined immunodeficien...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12604777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437964100 |
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