Schwann Cell-Specific Ablation of Laminin γ1 Causes Apoptosis and Prevents Proliferation

To investigate the function of laminin in peripheral nerve development, we specifically disrupted the laminin γ1 gene in Schwann cells. Disruption of laminin γ1 gene expression resulted in depletion of all other laminin chains known to be expressed in Schwann cells. Schwann cells lacking laminin do...

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Bibliographische Detailangaben
Hauptverfasser: Yu, Wei-Ming, Feltri, M. Laura, Wrabetz, Lawrence, Strickland, Sidney, Chen, Zu-Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2005
Schlagworte:
Development/Plasticity/Repair
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513628/
https://ncbi.nlm.nih.gov/pubmed/15872093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5032-04.2005
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