Schwann Cell-Specific Ablation of Laminin γ1 Causes Apoptosis and Prevents Proliferation

To investigate the function of laminin in peripheral nerve development, we specifically disrupted the laminin γ1 gene in Schwann cells. Disruption of laminin γ1 gene expression resulted in depletion of all other laminin chains known to be expressed in Schwann cells. Schwann cells lacking laminin do...

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Bibliographic Details
Main Authors: Yu, Wei-Ming, Feltri, M. Laura, Wrabetz, Lawrence, Strickland, Sidney, Chen, Zu-Lin
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2005
Subjects:
Development/Plasticity/Repair
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513628/
https://ncbi.nlm.nih.gov/pubmed/15872093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5032-04.2005
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