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Subfamily logos: visualization of sequence deviations at alignment positions with high information content

BACKGROUND: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserved positions can then be mutated and experimentally analyzed. However, identification of such sites is tedious because aut...

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Bibliographic Details
Main Author: Beitz, Eric
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513608/
https://ncbi.nlm.nih.gov/pubmed/16790056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-313
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