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Subfamily logos: visualization of sequence deviations at alignment positions with high information content

BACKGROUND: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserved positions can then be mutated and experimentally analyzed. However, identification of such sites is tedious because aut...

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Detalhes bibliográficos
Autor principal: Beitz, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513608/
https://ncbi.nlm.nih.gov/pubmed/16790056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-313
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