Detection of atovaquone-proguanil resistance conferring mutations in Plasmodium falciparum cytochrome b gene in Luanda, Angola

BACKGROUND: The fixed dose combination atovaquone-proguanil is a recently introduced antimalarial for treatment and prophylaxis of Plasmodium falciparum malaria. It is highly effective with a good tolerability profile and a convenient prophylactic regimen. Nevertheless, cases of treatment failure ha...

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Hlavní autoři: Pimentel, Sónia, Nogueira, Fátima, Benchimol, Carla, Quinhentos, Vatúsia, Bom, Joana, Varandas, Luís, do Rosário, Virgílio, Bernardino, Luís
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513587/
https://ncbi.nlm.nih.gov/pubmed/16597338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-5-30
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