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Atomic-level observation of macromolecular crowding effects: Escape of a protein from the GroEL cage
Experimental work has demonstrated that the efficient operation of the GroEL-GroES chaperonin machinery is sensitive to the presence of macromolecular crowding agents. Here, I describe atomically detailed computer simulations that provide a microscopic view of how crowding effects are exerted. Simul...
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| Glavni autor: | |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
2003
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151342/ https://ncbi.nlm.nih.gov/pubmed/12601146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0535055100 |
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