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Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains: A structural prototype for diversity in integrin signaling

The cytoplasmic domains (tails) of heterodimeric integrin adhesion receptors mediate integrins' biological functions by binding to cytoplasmic proteins. Most integrin β tails contain one or two NPXY/F motifs that can form β turns. These motifs are part of a canonical recognition sequence for phospho...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Calderwood, David A., Fujioka, Yosuke, de Pereda, Jose M., García-Alvarez, Begoña, Nakamoto, Tetsuya, Margolis, Ben, McGlade, C. Jane, Liddington, Robert C., Ginsberg, Mark H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12606711/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.262791999
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