Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains: A structural prototype for diversity in integrin signaling

The cytoplasmic domains (tails) of heterodimeric integrin adhesion receptors mediate integrins' biological functions by binding to cytoplasmic proteins. Most integrin β tails contain one or two NPXY/F motifs that can form β turns. These motifs are part of a canonical recognition sequence for ph...

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Bibliographische Detailangaben
Hauptverfasser: Calderwood, David A., Fujioka, Yosuke, de Pereda, Jose M., García-Alvarez, Begoña, Nakamoto, Tetsuya, Margolis, Ben, McGlade, C. Jane, Liddington, Robert C., Ginsberg, Mark H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151330/
https://ncbi.nlm.nih.gov/pubmed/12606711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262791999
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