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Synergistic enhancement of bone formation and healing by stem cell–expressed VEGF and bone morphogenetic protein-4
We investigated the interaction between angiogenic and osteogenic factors in bone formation and bone healing with ex vivo gene therapy using muscle-derived stem cells genetically engineered to express human bone morphogenetic protein-4 (BMP4), VEGF, or VEGF-specific antagonist (soluble Flt1). Our re...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151123/ https://ncbi.nlm.nih.gov/pubmed/12235106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15153 |
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