In vivo bradykinin B2 receptor activation reduces renal fibrosis

Angiotensin-converting enzyme (ACE) inhibitors reduce the progression of various fibrotic renal diseases both in humans and in animal models. Unilateral ureteral obstruction (UUO) is an animal model of accelerated renal tubulointerstitial fibrosis that is attenuated by ACE inhibition. Although ACE i...

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Hauptverfasser: Schanstra, Joost P., Neau, Eric, Drogoz, Pascale, Arevalo Gomez, Miguel A., Lopez Novoa, José Miguel, Calise, Denis, Pecher, Christiane, Bader, Michael, Girolami, Jean-Pierre, Bascands, Jean-Loup
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2002
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151090/
https://ncbi.nlm.nih.gov/pubmed/12163456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15493
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