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GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction
Signal transducer and activator of transcription 3 (Stat3) is a latent cytoplasmic transcription factor that can be activated by cytokines and growth factors. Stat3 plays important roles in cell growth, anti-apoptosis and cell transformation, and is constitutively active in various cancers. We exami...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151078/ https://ncbi.nlm.nih.gov/pubmed/12628925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg135 |
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