Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

The COP9 signalosome (CSN) purified from human erythrocytes possesses kinase activity that phosphoryl ates proteins such as c-Jun and p53 with consequence for their ubiquitin (Ub)-dependent degradation. Here we show that protein kinase CK2 (CK2) and protein kinase D (PKD) co-purify with CSN. Immunop...

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Detalhes bibliográficos
Main Authors: Uhle, Stefan, Medalia, Ohad, Waldron, Richard, Dumdey, Renate, Henklein, Peter, Bech-Otschir, Dawadschargal, Huang, Xiaohua, Berse, Matthias, Sperling, Joseph, Schade, Rüdiger, Dubiel, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151059/
https://ncbi.nlm.nih.gov/pubmed/12628923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg127
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