Essential role of Gas6 for glomerular injury in nephrotoxic nephritis

Growth-arrest specific gene 6 (Gas6) is a vitamin K–dependent growth factor for mesangial and epithelial cells. To investigate whether Gas6 is essential for progressive glomerular injury, we constructed Gas6(–/–) mice and examined the role of Gas6 in accelerated nephrotoxic nephritis (NTN), a model...

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Autors principals: Yanagita, Motoko, Ishimoto, Yoshikazu, Arai, Hidenori, Nagai, Kojiro, Ito, Tsuyoshi, Nakano, Toru, Salant, David J., Fukatsu, Atsushi, Doi, Toshio, Kita, Toru
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151046/
https://ncbi.nlm.nih.gov/pubmed/12122116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14861
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