Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis

Copolymer 1 (Cop 1, Copaxone [Teva Marion Partners, Kansas City, Missouri, USA]), a random amino acid copolymer of tyrosine (Y), glutamic acid (E), alanine (A), and lysine (K), reduces the frequency of relapses by 30% in relapsing-remitting multiple sclerosis (MS) patients. In the present study, nov...

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Pubblicato in:	J Clin Invest
Autori principali:	Fridkis-Hareli, Masha, Santambrogio, Laura, Stern, Joel N.H., Fugger, Lars, Brosnan, Celia, Strominger, Jack L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151016/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12070311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI15402
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