Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair

Preclinical and clinical studies suggest a possible role for cyclooxygenases in bone repair and create concerns about the use of nonsteroidal antiinflammatory drugs in patients with skeletal injury. We utilized wild-type, COX-1(–/–), and COX-2(–/–) mice to demonstrate that COX-2 plays an essential r...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Xinping, Schwarz, Edward M., Young, Donald A., Puzas, J. Edward, Rosier, Randy N., O’Keefe, Regis J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2002
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC151001/
https://ncbi.nlm.nih.gov/pubmed/12045254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15681
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk