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p53 negatively regulates intestinal immunity by delaying mucosal T cell cycling

To mount an effective immune response, T cells must divide in response to antigen contact. To maintain tolerance, mucosal lamina propria T cells (LPTs) may adapt their cycling to an antigen-rich gut stimulatory environment. Here, we compared the cell cycle kinetics of LPTs and peripheral blood T cel...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphov: Sturm, Andreas, Itoh, Jugoh, Jacobberger, James W., Fiocchi, Claudio
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical Investigation 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150997/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12045262/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14967
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