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p53 negatively regulates intestinal immunity by delaying mucosal T cell cycling

To mount an effective immune response, T cells must divide in response to antigen contact. To maintain tolerance, mucosal lamina propria T cells (LPTs) may adapt their cycling to an antigen-rich gut stimulatory environment. Here, we compared the cell cycle kinetics of LPTs and peripheral blood T cel...

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Detalhes bibliográficos
Main Authors: Sturm, Andreas, Itoh, Jugoh, Jacobberger, James W., Fiocchi, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150997/
https://ncbi.nlm.nih.gov/pubmed/12045262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14967
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