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Deficient natural killer cell cytotoxicity in patients with IKK-γ/NEMO mutations

NF-κB essential modifier (NEMO), also known as IKK-γ, is a member of the I-κB kinase complex responsible for phosphorylating I-κB, allowing the release and activation of NF-κB. Boys with an expressed NEMO mutation have an X-linked syndrome characterized by hypohidrotic ectodermal dysplasia with immu...

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Published in:J Clin Invest
Main Authors: Orange, Jordan S., Brodeur, Scott R., Jain, Ashish, Bonilla, Francisco A., Schneider, Lynda C., Kretschmer, Roberto, Nurko, Samuel, Rasmussen, Wendy L., Köhler, Julia R., Gellis, Stephen E., Ferguson, Betsy M., Strominger, Jack L., Zonana, Jonathan, Ramesh, Narayanaswamy, Ballas, Zuhair K., Geha, Raif S.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2002
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150995/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12045264/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14858
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