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Activation of the MEF2 transcription factor in skeletal muscles from myotonic mice

Becker syndrome, a recessive nondystrophic myotonia caused by mutations in the chloride channel 1 gene (CLCN1), is characterized by delayed muscle relaxation after contraction. The ADR (arrested development of righting response) mouse is an animal model for Becker syndrome. Skeletal muscles from ADR...

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Bibliographic Details
Main Authors: Wu, Hai, Olson, Eric N.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC150985/
https://ncbi.nlm.nih.gov/pubmed/12021248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15417
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