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The inhibitory action of some antimalarial drugs and related compounds on the hexokinase of yeast and of plasmodium berghei
Of various antimalarial compounds tested, only proguanil failed to inhibit yeast hexokinase. The metabolite of proguanil, 10,580, was an effective inhibitor. Some compounds tested which were without antimalarial activity were potent inhibitors of yeast hexokinase. The degree of inhibition increased...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1957
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1509652/ https://ncbi.nlm.nih.gov/pubmed/13413145 |
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