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The inhibitory action of some antimalarial drugs and related compounds on the hexokinase of yeast and of plasmodium berghei

Of various antimalarial compounds tested, only proguanil failed to inhibit yeast hexokinase. The metabolite of proguanil, 10,580, was an effective inhibitor. Some compounds tested which were without antimalarial activity were potent inhibitors of yeast hexokinase. The degree of inhibition increased...

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Detalhes bibliográficos
Main Authors: Fraser, Dorothy M., Kermack, W. O.
Formato: Artigo
Idioma:Inglês
Publicado em: 1957
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1509652/
https://ncbi.nlm.nih.gov/pubmed/13413145
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