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Ectopic expression of KCNE3 accelerates cardiac repolarization and abbreviates the QT interval
Regulatory subunit KCNE3 (E3) interacts with KCNQ1 (Q1) in epithelia, regulating its activation kinetics and augmenting current density. Since E3 is expressed weakly in the heart, we hypothesized that ectopic expression of E3 in cardiac myocytes might abbreviate action potential duration (APD) by in...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150950/ https://ncbi.nlm.nih.gov/pubmed/11956246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15062 |
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