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The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes

Patients with nail-patella syndrome often suffer from a nephropathy, which ultimately results in chronic renal failure. The finding that this disease is caused by mutations in the transcription factor LMX1B, which in the kidney is expressed exclusively in podocytes, offers the opportunity for a bett...

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Udgivet i:J Clin Invest
Principais autores: Rohr, Claudia, Prestel, Jürgen, Heidet, Laurence, Hosser, Hiltraud, Kriz, Wilhelm, Johnson, Randy L., Antignac, Corinne, Witzgall, Ralph
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11956245/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13961
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