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The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes

Patients with nail-patella syndrome often suffer from a nephropathy, which ultimately results in chronic renal failure. The finding that this disease is caused by mutations in the transcription factor LMX1B, which in the kidney is expressed exclusively in podocytes, offers the opportunity for a bett...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Rohr, Claudia, Prestel, Jürgen, Heidet, Laurence, Hosser, Hiltraud, Kriz, Wilhelm, Johnson, Randy L., Antignac, Corinne, Witzgall, Ralph
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11956245/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13961
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