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Thymocyte emigration is mediated by active movement away from stroma-derived factors

T cells leave the thymus at a specific time during differentiation and do not return despite elaboration of known T cell chemoattractants by thymic stroma. We observed differentiation stage–restricted egress of thymocytes from an artificial thymus in which vascular structures or hemodynamics could n...

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Detalhes bibliográficos
Main Authors: Poznansky, Mark C., Olszak, Ivona T., Evans, Richard H., Wang, Zhengyu, Foxall, Russell B., Olson, Douglas P., Weibrecht, Kathryn, Luster, Andrew D., Scadden, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150941/
https://ncbi.nlm.nih.gov/pubmed/11956248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13853
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