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GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

Insulin-dependent type 1 diabetes is an autoimmune disease mediated by T lymphocytes recognizing pancreatic islet cell antigens. Glutamic acid decarboxylase 65 (GAD65) appears to be an important autoantigen in the disease. However, T cells from both patients with type 1 diabetes and healthy subjects...

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Détails bibliographiques
Auteurs principaux: Viglietta, Vissia, Kent, Sally C., Orban, Tihamer, Hafler, David A.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC150925/
https://ncbi.nlm.nih.gov/pubmed/11927616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14114
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