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An Analysis of the Cross-Reactivity of Autoantibodies to GAD65 and GAD67 in Diabetes

BACKGROUND: Autoantibodies to GAD65 (anti-GAD65) are present in the sera of 70–80% of patients with type 1 diabetes (T1D), but antibodies to the structurally similar 67 kDa isoform GAD67 are rare. Antibodies to GAD67 may represent a cross-reactive population of anti-GAD65, but this has not been form...

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Autors principals: Jayakrishnan, Bindu, Hoke, David E., Langendorf, Christopher G., Buckle, Ashley M., Rowley, Merrill J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072979/
https://ncbi.nlm.nih.gov/pubmed/21494613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018411
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