The α(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction

To investigate the physiological role of the α(1D)-adrenergic receptor (α(1D)-AR) subtype, we created mice lacking the α(1D)-AR (α(1D)(–/–)) by gene targeting and characterized their cardiovascular function. In α(1D)(–/–) mice, the RT-PCR did not detect any transcript of the α(1D)-AR in any tissue e...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Tanoue, Akito, Nasa, Yoshihisa, Koshimizu, Takaaki, Shinoura, Hitomi, Oshikawa, Sayuri, Kawai, Takayuki, Sunada, Sachie, Takeo, Satoshi, Tsujimoto, Gozoh
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 2002
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11901185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14001
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