The α(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction

To investigate the physiological role of the α(1D)-adrenergic receptor (α(1D)-AR) subtype, we created mice lacking the α(1D)-AR (α(1D)(–/–)) by gene targeting and characterized their cardiovascular function. In α(1D)(–/–) mice, the RT-PCR did not detect any transcript of the α(1D)-AR in any tissue e...

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Hlavní autoři: Tanoue, Akito, Nasa, Yoshihisa, Koshimizu, Takaaki, Shinoura, Hitomi, Oshikawa, Sayuri, Kawai, Takayuki, Sunada, Sachie, Takeo, Satoshi, Tsujimoto, Gozoh
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150908/
https://ncbi.nlm.nih.gov/pubmed/11901185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14001
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