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Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis

The role of the renin-angiotensin system (RAS) in angiogenesis is little known. Here, we show that the angiotensin II (ATII) type 1 (AT1) receptor plays an important role in ischemia-induced angiogenesis. Well-developed collateral vessels and angiogenesis were observed in wild-type (WT) mice in resp...

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Autori principali: Sasaki, Ken-ichiro, Murohara, Toyoaki, Ikeda, Hisao, Sugaya, Takeshi, Shimada, Toshifumi, Shintani, Satoshi, Imaizumi, Tsutomu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC150887/
https://ncbi.nlm.nih.gov/pubmed/11877468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13055
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