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CD4(+) T cells specific to a glomerular basement membrane antigen mediate glomerulonephritis

Ab-mediated mechanisms have been considered the major causes of glomerulonephritis (GN). However, recent studies suggest that T cells may be more important in mediating GN. To investigate the effects of antigen-specific CD4(+) T cells, we generated Th1 cell lines specific for this antigen from rats...

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Wu, Jean, Hicks, John, Borillo, Jason, Glass, William F., Lou, Ya-Huan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854324/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13876
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