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CD4(+) T cells specific to a glomerular basement membrane antigen mediate glomerulonephritis

Ab-mediated mechanisms have been considered the major causes of glomerulonephritis (GN). However, recent studies suggest that T cells may be more important in mediating GN. To investigate the effects of antigen-specific CD4(+) T cells, we generated Th1 cell lines specific for this antigen from rats...

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Detalhes bibliográficos
Main Authors: Wu, Jean, Hicks, John, Borillo, Jason, Glass, William F., Lou, Ya-Huan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150874/
https://ncbi.nlm.nih.gov/pubmed/11854324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13876
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