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Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis

Leukocyte recruitment in inflammation is critical for host defense, but excessive accumulation of inflammatory cells can lead to tissue damage. Neutrophil-derived serine proteases (cathepsin G [CG], neutrophil elastase [NE], and proteinase 3 [PR3]) are expressed specifically in mature neutrophils an...

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Detalles Bibliográficos
Main Authors: Adkison, April M., Raptis, Sofia Z., Kelley, Diane G., Pham, Christine T.N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC150852/
https://ncbi.nlm.nih.gov/pubmed/11827996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13462
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