Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis

BACKGROUND: The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp virulence, we performed a comparative genomic analysis of Bp K96243 and B. thailandensis (Bt) E264, a closely r...

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Main Authors: Yu, Yiting, Kim, H Stanley, Chua, Hui Hoon, Lin, Chi Ho, Sim, Siew Hoon, Lin, Daoxun, Derr, Alan, Engels, Reinhard, DeShazer, David, Birren, Bruce, Nierman, William C, Tan, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508146/
https://ncbi.nlm.nih.gov/pubmed/16725056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-6-46
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