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Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

Ingestion of apoptotic cells in vitro by macrophages induces TGF-β1 secretion, resulting in an anti-inflammatory effect and suppression of proinflammatory mediators. Here, we show in vivo that direct instillation of apoptotic cells enhanced the resolution of acute inflammation. This enhancement appe...

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書目詳細資料
發表在:J Clin Invest
Principais autores: Huynh, Mai-Lan N., Fadok, Valerie A., Henson, Peter M.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2002
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11781349/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11638
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