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Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

Ingestion of apoptotic cells in vitro by macrophages induces TGF-β1 secretion, resulting in an anti-inflammatory effect and suppression of proinflammatory mediators. Here, we show in vivo that direct instillation of apoptotic cells enhanced the resolution of acute inflammation. This enhancement appe...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:J Clin Invest
Үндсэн зохиолчид: Huynh, Mai-Lan N., Fadok, Valerie A., Henson, Peter M.
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: American Society for Clinical Investigation 2002
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11781349/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11638
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