Retinoic Acid Repression of Bone Morphogenetic Protein 4 in Inner Ear Development

Bone morphogenetic protein 4 (BMP4) and retinoic acid are important for normal development of the inner ear, but whether they are linked mechanistically is not known. BMP4 antagonists disrupt semicircular canal formation, as does exposure to retinoic acid. We demonstrate that retinoic acid directly...

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Bibliographic Details
Main Authors: Thompson, Deborah L., Gerlach-Bank, Lisa M., Barald, Kate F., Koenig, Ronald J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC150746/
https://ncbi.nlm.nih.gov/pubmed/12640113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2277-2286.2003
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