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Retinoic Acid Repression of Bone Morphogenetic Protein 4 in Inner Ear Development

Bone morphogenetic protein 4 (BMP4) and retinoic acid are important for normal development of the inner ear, but whether they are linked mechanistically is not known. BMP4 antagonists disrupt semicircular canal formation, as does exposure to retinoic acid. We demonstrate that retinoic acid directly...

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Autors principals: Thompson, Deborah L., Gerlach-Bank, Lisa M., Barald, Kate F., Koenig, Ronald J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150746/
https://ncbi.nlm.nih.gov/pubmed/12640113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2277-2286.2003
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