Gab3-Deficient Mice Exhibit Normal Development and Hematopoiesis and Are Immunocompetent

Gab proteins are intracellular scaffolding and docking molecules involved in signaling pathways mediated by various growth factor, cytokine, or antigen receptors. Gab3 has been shown to act downstream of the macrophage colony-stimulating factor receptor, c-Fms, and to be important for macrophage dif...

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Autors principals: Seiffert, Martina, Custodio, Joseph M., Wolf, Ingrid, Harkey, Michael, Liu, Yan, Blattman, Joseph N., Greenberg, Philip D., Rohrschneider, Larry R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150735/
https://ncbi.nlm.nih.gov/pubmed/12640125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2415-2424.2003
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