Gab3-Deficient Mice Exhibit Normal Development and Hematopoiesis and Are Immunocompetent

Gab proteins are intracellular scaffolding and docking molecules involved in signaling pathways mediated by various growth factor, cytokine, or antigen receptors. Gab3 has been shown to act downstream of the macrophage colony-stimulating factor receptor, c-Fms, and to be important for macrophage dif...

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Bibliographic Details
Main Authors: Seiffert, Martina, Custodio, Joseph M., Wolf, Ingrid, Harkey, Michael, Liu, Yan, Blattman, Joseph N., Greenberg, Philip D., Rohrschneider, Larry R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC150735/
https://ncbi.nlm.nih.gov/pubmed/12640125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2415-2424.2003
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