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A Positive Autoregulatory Loop of LMP1 Expression and STAT Activation in Epithelial Cells Latently Infected with Epstein-Barr Virus

STAT3 and STAT5 are constitutively activated and nuclear in nasopharyngeal carcinoma (NPC) cells. In normal signaling, STATs are only transiently activated. To investigate whether Epstein-Barr virus (EBV), and in particular the protein LMP1, contributes to sustained STAT phosphorylation and activati...

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Vydáno v:J Virol
Hlavní autoři: Chen, Honglin, Hutt-Fletcher, Lindsey, Cao, Liang, Hayward, S. Diane
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150666/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12634372/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.7.4139-4148.2003
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