A Positive Autoregulatory Loop of LMP1 Expression and STAT Activation in Epithelial Cells Latently Infected with Epstein-Barr Virus

STAT3 and STAT5 are constitutively activated and nuclear in nasopharyngeal carcinoma (NPC) cells. In normal signaling, STATs are only transiently activated. To investigate whether Epstein-Barr virus (EBV), and in particular the protein LMP1, contributes to sustained STAT phosphorylation and activati...

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Autors principals: Chen, Honglin, Hutt-Fletcher, Lindsey, Cao, Liang, Hayward, S. Diane
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150666/
https://ncbi.nlm.nih.gov/pubmed/12634372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.7.4139-4148.2003
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