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Engineering the Transmissible Gastroenteritis Virus Genome as an Expression Vector Inducing Lactogenic Immunity

The genome of the coronavirus transmissible gastroenteritis virus (TGEV) has been engineered as an expression vector with an infectious cDNA. The vector led to the efficient (>40 μg/10(6) cells) and stable (>20 passages) expression of a heterologous gene (green fluorescent protein [GFP]), driv...

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Detalhes bibliográficos
Main Authors: Sola, Isabel, Alonso, Sara, Zúñiga, Sonia, Balasch, Mónica, Plana-Durán, Juan, Enjuanes, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150661/
https://ncbi.nlm.nih.gov/pubmed/12634392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.7.4357-4369.2003
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