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Treatment of Human Immunodeficiency Virus Type 1 Virions Depleted of Cyclophilin A by Natural Endogenous Reverse Transcription Restores Infectivity

We have previously shown that virions with nef deleted can be restored to wild-type infectivity by treatment to induce natural endogenous reverse transcription (NERT). Since Nef and cyclophilin A (CyPA) appear to act in similar ways on postentry events, we determined whether NERT treatment would res...

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Autori principali: Khan, Mahfuz, Garcia-Barrio, Minerva, Powell, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC150660/
https://ncbi.nlm.nih.gov/pubmed/12634401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.7.4431-4434.2003
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