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Chemosensitization of Human Renal Cell Cancer Using Antisense Oligonucleotides Targeting the Antiapoptotic Gene Clusterin

BACKGROUND: Renal cell cancer (RCC) is a chemoresistant disease with no active chemotherapeutic agent achieving objective response rates higher than 15%. Clusterin is a cell survival gene that increases in human renal tubular epithelial cells after various states of injury and disease. Downregulatio...

詳細記述

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書誌詳細
主要な著者: Zellweger, Tobias, Miyake, Hideaki, July, Laura V, Akbari, Majid, Kiyama, Satoshi, Gleave, Martin E
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505861/
https://ncbi.nlm.nih.gov/pubmed/11571636
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