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Therapeutic Efficacy of Adenoviral-Mediated p53 Gene Transfer Is Synergistically Enhanced by Combined Use of Antisense Oligodeoxynucleotide Targeting Clusterin Gene in a Human Bladder Cancer Model

To establish a more effective therapeutic strategy against advanced bladder cancer, we investigated the effects of combined treatment with antisense (AS) oligodeoxynucleotide (ODN) targeting the antiapoptotic gene clusterin and adenoviral-mediated p53 gene transfer (Ad5CMV-p53) using the human bladd...

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Detalhes bibliográficos
Main Authors: Miyake, Hideaki, Yamanaka, Kazuki, Muramaki, Mototsugu, Hara, Isao, Gleave, Martin E
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501130/
https://ncbi.nlm.nih.gov/pubmed/15802022
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