Detection of MYCN Gene Amplification in Neuroblastoma by Fluorescence In Situ Hybridization: A Pediatric Oncology Group Study

To assess the utility of fluorescence in situ hybridization (FISH) for analysis of MYCN gene amplification in neuroblastoma, we compared this assay with Southern blot analysis using tumor specimens collected from 232 patients with presenting characteristics typical of this disease. The FISH techniqu...

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Main Authors: Mathew, Prasad, Valentine, Marcus B, Bowman, Laura C, Rowe, Susan T, Nash, Michael B, Valentine, Virginia A, Cohn, Susan L, Castleberry, Robert P, Brodeur, Garrett M, Look, A Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505416/
https://ncbi.nlm.nih.gov/pubmed/11420745
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