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Detection of MYCN Gene Amplification in Neuroblastoma by Fluorescence In Situ Hybridization: A Pediatric Oncology Group Study

To assess the utility of fluorescence in situ hybridization (FISH) for analysis of MYCN gene amplification in neuroblastoma, we compared this assay with Southern blot analysis using tumor specimens collected from 232 patients with presenting characteristics typical of this disease. The FISH techniqu...

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Détails bibliographiques
Auteurs principaux: Mathew, Prasad, Valentine, Marcus B, Bowman, Laura C, Rowe, Susan T, Nash, Michael B, Valentine, Virginia A, Cohn, Susan L, Castleberry, Robert P, Brodeur, Garrett M, Look, A Thomas
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505416/
https://ncbi.nlm.nih.gov/pubmed/11420745
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