Suppression of Angiogenesis and Therapy of Human Colon Cancer Liver Metastasis by Systemic Administration of Interferon-α

The purpose of this study was to determine whether systemic administration of interferon-alpha (IFN-α) can inhibit liver metastasis produced in nude mice by human colon cancer cells. KM12L4 (IFN-α-sensitive) or KM12L4 IFN(R) (IFN-α-resistant) cells were injected into the spleen of nude mice. Seven d...

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Detalhes bibliográficos
Main Authors: Ozawa, Shutaro, Shinohara, Hisashi, Kanayama, Hiro-omi, Bruns, Christiane J, Bucana, Corazon D, Ellis, Lee M, Davis, Darren W, Fidler, Isaiah J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505412/
https://ncbi.nlm.nih.gov/pubmed/11420751
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